Parkinson’s Disease: Symptoms and Causes
Parkinson’s disease (PD) is a progressive neurodegenerative disorder that chiefly impacts movement. It happens when certain brain cells (neurons) in the basal ganglia – the area controlling movement – deteriorate or die. These neurons normally produce dopamine, a neurotransmitter vital for smooth, controlled muscle activity. As dopamine levels drop due to cell loss, the brain’s ability to regulate movement decreases. This leads to the classic motor symptoms of Parkinson’s:
- Tremors: Typically a resting tremor, such as a pill-rolling tremor of the hands, which means shaking that is most noticeable when your limb is at rest. Tremors often start on one side (like one hand) and may spread to the other side over time.
- Bradykinesia (Slowness of movement): You may find it takes longer to perform simple movements. Walking may become slow or shuffling, and activities like buttoning a shirt are more difficult due to reduced dexterity.
- Rigidity: Stiffness in the limbs or neck, causing a feeling of muscle tension and resistance to movement. This can lead to muscle aches and a stooped posture.
- Postural Instability: Balance problems and a tendency to stoop or have difficulty with coordination, which can increase the risk of falls.
People with Parkinson’s may also experience non-motor symptoms like a reduced sense of smell, constipation, sleep disturbances, mood changes, and cognitive issues. Early warning signs can include chronic constipation, loss of smell, or REM sleep behavior disorder. Motor signs start subtly, like a slight tremor or smaller handwriting.
Parkinson’s disease is idiopathic for most, meaning its cause is unknown. It’s often a mix of genetic and environmental factors. Some cases are hereditary, while others are linked to toxins or aging. The main issue is dopamine-producing cell loss, leading to gradual symptom progression.
Diagnosis and Evaluation of Movement Disorders
Accurate and early diagnosis of movement disorders is crucial. At HealthHub, our neurologists perform thorough evaluations to diagnose Parkinson’s disease. This involves a detailed medical history, symptom review, and neurological examination, focusing on muscle tone, reflexes, coordination, and gait.
To rule out other conditions, we may order blood tests and MRI scans, and in some cases, a Dopamine Transporter (DaT) scan to confirm reduced dopamine activity, indicative of Parkinson’s. We also differentiate between tremors: essential tremors occur during movement, while Parkinsonian tremors occur at rest.
Follow-up appointments are valuable to observe the evolution of symptoms and confirm the diagnosis. We emphasize clear communication, ensuring you understand your condition and treatment options. For those diagnosed elsewhere, we offer second opinions and comprehensive reviews.